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CMP-legionaminate biosynthesis I

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
GDP-alpha-N-acetyl-D-glucosamine <=> GDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hexos-4-ulose + H2O 4.2.1

GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + GDP + H+ 3.2.1

GDP-4-amino-4,6-dideoxy-alpha-D-N-acetylglucosamine + acetyl-CoA <=> H+ + GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose + CoA 2.3.1

beta-D-fructose_6-phosphate + L-glutamine <=> D-glucose_6-phosphate + L-glutamate 2.6.1.16 glutamine---fructose-6-phosphate transaminase (isomerizing)

GDP-glucosamine + acetyl-CoA <=> H+ + GDP-alpha-N-acetyl-D-glucosamine + CoA 2.3.1

GDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hexos-4-ulose + L-glutamate <=> GDP-4-amino-4,6-dideoxy-alpha-D-N-acetylglucosamine + 2-oxoglutarate 2.6.1

H+ + alpha-D-glucosamine_1-phosphate + GTP <=> GDP-glucosamine + diphosphate 2.7.7
2.7.7.13 mannose-1-phosphate guanylyltransferase
2.7.7.30 fucose-1-phosphate guanylyltransferase
2.7.7.34 glucose-1-phosphate guanylyltransferase




CTP + N,N'-diacetyllegionaminate <=> CMP-N,N''-diacetyllegionaminate + diphosphate 2.7.7.82 CMP-N,N'-diacetyllegionaminic acid synthase

2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + phosphoenolpyruvate + H2O <=> N,N'-diacetyllegionaminate + phosphate 2.5.1.101 N,N'-diacetyllegionaminate synthase

D-glucose_6-phosphate <=> alpha-D-glucosamine_1-phosphate 5.4.2.10 phosphoglucosamine mutase
5.4.2.13 phosphogalactosamine mutase
5.4.2.2 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
5.4.2.3 phosphoacetylglucosamine mutase
5.4.2.8 phosphomannomutase





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